John F Seymour Selected Research

Protein-Tyrosine Kinases (Tyrosine Kinase)

6/2012	Rapid detection of FLT3 exon 20 tyrosine kinase domain mutations in patients with acute myeloid leukemia by high-resolution melting analysis.
10/2003	ALK-positive diffuse large B-cell lymphoma is associated with Clathrin-ALK rearrangements: report of 6 cases.

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John F Seymour Research Topics

Disease

43	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 11/2022 - 10/2003
42	Neoplasms (Cancer) 05/2022 - 02/2002
30	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2022 - 02/2004
22	Lymphoma (Lymphomas) 03/2022 - 06/2003
18	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2021 - 02/2002
17	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2022 - 04/2005
16	Infections 01/2022 - 11/2004
15	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 10/2022 - 02/2002
15	Disease Progression 01/2022 - 07/2002
15	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 10/2021 - 10/2003
13	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2019 - 03/2009
12	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 12/2018 - 07/2003
11	Residual Neoplasm 01/2022 - 07/2013
10	Neutropenia 01/2021 - 09/2006
8	Multiple Myeloma 01/2022 - 07/2003
7	B-Cell Lymphoma (Lymphoma, B Cell) 01/2022 - 07/2005
6	Waldenstrom Macroglobulinemia (Macroglobulinemia) 10/2020 - 03/2005
6	Tumor Lysis Syndrome 10/2018 - 03/2007
6	Hodgkin Disease (Hodgkin's Disease) 06/2014 - 03/2002
5	Thrombocytopenia (Thrombopenia) 01/2021 - 09/2006
5	Cytopenia 01/2021 - 07/2005
5	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 06/2015 - 07/2005
4	Leukemia 12/2018 - 08/2010
4	Febrile Neutropenia 03/2018 - 08/2004
4	Hematologic Neoplasms (Hematological Malignancy) 08/2014 - 12/2005
3	Atrial Fibrillation 11/2021 - 12/2014
3	Anemia 01/2021 - 04/2010
3	Chromosome Aberrations (Chromosome Abnormalities) 01/2020 - 01/2007
3	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 01/2019 - 04/2013
3	Sepsis (Septicemia) 01/2019 - 04/2008
3	Acute Promyelocytic Leukemia 05/2017 - 08/2012
3	Stomatitis 12/2014 - 07/2005
3	Refractory Anemia with Excess of Blasts (RAEM) 12/2010 - 04/2010
2	Fatigue 01/2022 - 04/2015
2	Dyspnea (Shortness of Breath) 01/2022 - 04/2015
2	Lymphadenopathy 11/2019 - 02/2012
2	Mouth Neoplasms (Oral Cancer) 04/2019 - 12/2017
2	Chronic Disease (Chronic Diseases) 04/2019 - 11/2018
2	Second Primary Neoplasms (Neoplasms, Second) 10/2018 - 03/2007
2	Bacterial Infections (Bacterial Infection) 10/2017 - 05/2007
2	Mycoses (Diseases, Fungus) 02/2016 - 07/2013
2	Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) 01/2015 - 08/2013
2	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 09/2014 - 10/2003
2	Mucositis 08/2014 - 07/2005
2	Eosinophilia 06/2014 - 01/2007

Drug/Important Bio-Agent (IBA)

48	Rituximab (Mabthera)FDA Link 01/2022 - 02/2004
41	venetoclaxIBA 11/2022 - 02/2013
25	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 05/2004
24	fludarabineIBA 05/2016 - 02/2002
19	Azacitidine (5 Azacytidine)FDA Link 01/2022 - 03/2009
12	Imatinib Mesylate (Gleevec)FDA Link 06/2014 - 07/2003
10	ibrutinibIBA 10/2022 - 12/2014
9	Cytarabine (Cytosar-U)FDA LinkGeneric 05/2017 - 02/2002
8	Proteins (Proteins, Gene)FDA Link 11/2022 - 10/2003
8	Vincristine (Oncovin)FDA LinkGeneric 01/2021 - 06/2005
8	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 09/2008
7	obinutuzumabIBA 05/2020 - 01/2015
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2006
6	Bendamustine Hydrochloride FDA Link 01/2022 - 03/2018
6	Pharmaceutical PreparationsIBA 04/2019 - 01/2006
5	Agammaglobulinaemia Tyrosine KinaseIBA 10/2022 - 01/2020
5	Monoclonal AntibodiesIBA 01/2022 - 01/2006
5	GalliumIBA 05/2020 - 03/2002
5	AnthracyclinesIBA 07/2019 - 10/2008
5	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2017 - 06/2003
4	Prednisone (Sone)FDA LinkGeneric 10/2018 - 12/2013
4	Thalidomide (Thalomid)FDA Link 01/2017 - 07/2003
4	Melphalan (Alkeran)FDA LinkGeneric 01/2017 - 07/2005
4	Anti-Bacterial Agents (Antibiotics)IBA 08/2014 - 05/2007
4	Dexamethasone (Maxidex)FDA LinkGeneric 12/2011 - 06/2005
4	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 05/2007 - 07/2002
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2006
3	zanubrutinibIBA 10/2020 - 12/2019
3	Tyrosine Kinase InhibitorsIBA 12/2018 - 12/2017
3	Etoposide (VP 16)FDA LinkGeneric 05/2017 - 07/2005
3	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 05/2017 - 08/2012
3	navitoclaxIBA 09/2015 - 02/2012
3	Arsenic Trioxide (Trisenox)FDA Link 09/2015 - 08/2012
3	Dasatinib (BMS 354825)FDA Link 11/2011 - 03/2008
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 05/2008 - 09/2006
3	Mitoxantrone (Novantrone)FDA LinkGeneric 12/2006 - 11/2004
3	Alemtuzumab (Campath)FDA Link 01/2006 - 12/2004
2	Prednisolone (Predate)FDA LinkGeneric 01/2021 - 05/2008
2	AntigensIBA 01/2021 - 10/2006
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2018 - 07/2005
2	Daunorubicin (Cerubidine)FDA LinkGeneric 05/2017 - 05/2008
2	Carmustine (FIVB)FDA Link 01/2017 - 07/2005
2	Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA 06/2014 - 01/2007
2	Methotrexate (Mexate)FDA LinkGeneric 06/2014 - 06/2011
2	Bortezomib (Velcade)FDA Link 07/2013 - 12/2011
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 06/2012 - 10/2003

Therapy/Procedure

78	Therapeutics 11/2022 - 06/2003
37	Drug Therapy (Chemotherapy) 10/2022 - 02/2004
12	Stem Cell Transplantation 12/2020 - 07/2005
8	Radiotherapy 01/2021 - 06/2003
7	Salvage Therapy 01/2015 - 02/2002
4	Combination Drug Therapy (Combination Chemotherapy) 01/2022 - 11/2004
4	Aftercare (After-Treatment) 01/2016 - 09/2006
2	Immunotherapy 01/2020 - 05/2008
2	Consolidation Chemotherapy 12/2016 - 02/2016